.25 ml of tirzepatide Dosage help : r/tirzepatidecompound Semaglutide & Tirzepatide Dosing Guide:

Those most likely to be deficient in Vit B12: Vegans Vegetarians Those that suffer with Stomach acid, intestinal/bowel disorders Those over 60+ Individuals who adhere to a strict vegetarian or vegan diet may not receive enough vitamin B12

It changes some of the programming when its too close, Borbely warns

Future investigation using verified formulations and prospective clinical study designs is necessary to determine whether peptide-based therapies can be safely and meaningfully integrated into orthopedic care.

If you continue to run, but cant stop yourself from consistently overdoing it and falling into that boom-bust cycle, then it might be worth considering taking a break from running